抄録
Since August 1960, the authors carried out the common studies with Dr. Muneo Yokogawa and co-workers (Dept. of Parasitology, School of Medicine Chiba Univ.), on the treatment of human paragonimiasis applied Bitin (Tanabe Co.) and proved that Bitin is quite effective for this disease.
1) Administration and dosage: Usually 30-40mg/kg daily divided 2 or 3 doses after meals every other day for 10 days.
2) The antibody titers in complement fixation test were shown the tendency of decrease gradually and became negative during the period from 1 to 12 months after the completion of the treatment.
3) Most of the abnormal schadows found in chest X-ray films before the treatment showed the tendencies of disappearances or reductions immediately after the completion of the treatment and disappeared within 12 months.
4) No relapses were found in any cases from the results of follow-up examinations maximum for about 3 years after the completion of the treatment.
5) The side-effects such as diarrhea, abdominal pain, nausea, vomitting or urticardial erruption were found sometimes during the period of the administrations of Bitin, but they were all trancient and mild.
