抄録
In recent years, the pathogenesis of central nervous system complication caused by exanthematous infectious disease has been the subject of study by many investigators, while the definite conclusion has not been established yet.
In this report, the pathogenesis of the secondary encephalomyelitis was discussed based on the clinical observations of our own experienced cases which had developed central nervous system involvement due to measles and varicella, three cases and one case respectively.
As the other investigators had pointed out, the secondary encephalomyelitis was produced by not only so simple as neuroallergic reaction, but various kinds of pathological disturbances such as electrolyte unbalance, cerebral vascular damage, cerebral edema and cerebral anoxia, etc, would be related.
The fundamental principle of the treatment should be strongly symptomatic; i. e. maintenance of proper electrolyte balance, sufficient oxygen supply, anticonvulsant agent and antibiotics, while ACTH and steroids should not be the first choice and must be used from consideration of the clinical sign or course of the patient.
