抄録
We got the following fruits after we compared the minimal intercepting concentrations of mycobacterium tuberculosis of cycloserine on 196 Ogawa medium, Kirchner agar medium and Kirchner semi-solid agar medium.
1) When we judged the minimal intercepting concentration of mycobacterium tuberculosis on 1% Ogawa medium after four weeks and on Kirchner semi-solid agar medium after three weeks, both of them were 20-3omcg/ml. So they were nearly coincided. But the minimal intercepting concentration of mycobacterium tuberculosis of Cycloserine on Kirchner agar medium was 50-75mcg/ml after four weeks. It was always higher than the former two media.
2) We determined that 1% Ogawa medium or Kirchner semisolid agar medium, whose minimal intercepting concentration of mycobacterium tuberculosis is low, is suitable to routine drug resistance determination of Cycloserine.