医療
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
ニツソールの医学的研究
坪井 澄也
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ジャーナル フリー

1967 年 21 巻 5 号 p. 612-615

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抄録
Nissol is a new agricultural chemicals developed by Nippon Soda Co. Ltd, as a miticide. It is an organic flourine compound, chemically named N-Methyl-N-(1-naphthyl) fluoroacetamide with a following chemical formula.
I studied the antidotal virtue to Nissol intoxication on the living body and results was as follows:
1) From the hematological point of view I found a decrease of leucocytes in rabbits by Nissol injection. Some drugs, such as Sodii thiosulfate, Gluthrtione, Cystine, Paniltin, Mercapto, Thiola, Methionine, Antabuse, Thiourea, Vitamin B1, Alinamin, Thioctic acid, Chlorpromazine, Vitamin B6, Orotic acid, Vitamin C, Glucose, Glucuronic acid, Strong Neominophagen C, Glycyrrhizine, Acetamide and Monacetin are effective.
2) No significant differences were found in the blood-sugar level of the rabbit betweenn the Nissol injection and the control group.
3) There is a rectilinear relation between the survival time (t) and the Nissol concentration (C).
This data fits the Freundlich adsorption isotherm and this phenomenon is an adsorption as it applies to the Ostwald toxic equation.
4) Paramecium and Colibacillus are killed by concentrated Nissol.
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© 一般社団法人国立医療学会
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