肺癌を合併した塵肺症とその気管支上皮の病理組織学的研究

抄録

The histological site of occurenoe of pulmonary carcinoma is not clarified definitely so far, and the rate of incidence of pulmonary carcinoma among pneumoconiotic patientss seems differing from the dusts causing it, excepting the asbestosis. The latter is known to be accompanying malignant tumors in considerable rate.
We experienced 7 cases whichh were detected pulmonary carcinoma by autopsy among pneumoconiosis, including cases of silicosis, cases of asbestosis, one case of pyrophylite pneumoconiosis and a case of welders lung.
The details of each cases were described and in relation to the site of occurence we examined the bronchial epithet. Twenty to twenty-eight sections from the bronchial tree of each of 7 cases decribed above were studied microscopically and to compare with them pneumoconiotic lung without carcinoma, and as controls lungs from urban aged autopsy materials were examined.
Squamous metaplasia was detected in highest rate (19.3%) among asbestosis with cancer, and basal hyperplasia showed in considerably high levels (63.0) compared with other cases, as well, These histolgical findings detected significantly higher rates in carcinomotour cases compared with non carcinomotous pneumoconiotic lunges equally.