Abstract
To investigate the effect of Histalog and Gastrin on pancreas and gallbladder, the acid and HCO3 secretion after Histalog and Gastrin administration was determined in group including cases with gastric or duodenal ulcer, bile duct disorder, chronic gastritis and chronic pancreatitis.
The patient was determined the acid secretion with Histalog in advance and divided into four subgroups, hyperacidity, normo-acidity, hypoacidity and anacidity.
The effect of Histalog and Gastrin was investigated by the following two methods.
In the first method Histalog or Gastrin was injected immediately after pancreozymin secretion test, while in the second method before the pancreozymin Secretin test.
Irrespective of stimulant the first method showed increase of HCO3 output in anacidity group.
As additional finding the contraction of gallbladder after gastric administration was recognized.
From these results following conclusion was lead, that these stimulants have a direct action to pancreas and its effect was stronger in Gastrin than Histalog.
