抄録
Fluorescence corneal angiography is a modification of fluorescence fundus photography. This procedure is very useful in the analysis of vascularization of the cornea.
In this report, the author discussed the behavior of blood circulation at limbal and new-formed corneal capillaries examined by fluorescence corneal angiography.
Serial fluorescence corneal angiographs are chronologically divided into four stages. The first stage or prefilling phase, is the earliest time immediately after injection of dye when the dye has not yet reached capillaries. The dye then reaches capillaries and fill them. This stage is termed the capillary filling phase. The third phase of extravasation is the time when the dye leakage break out from capillaries. Finally, the dye leaking from capillaries diffuse into the surrounding tissue, and fluorescence gradually spread in all direction. This last stage is termed the phase of diffusion.
Fluorescence corneal angiographs of inflamed limbal capillaries and new formed corneal capillaries showed that intensity of the dye leakage from capillaries in proportion to that of inflammation.
The neovascularization in active processes can be differentiated unequivocally from the pannus depending on such findings as the arrangement of vessels, the shape of apex of capillary loops, and the mode of dye leakage.
