Japanese Journal of National Medical Services
Online ISSN : 1884-8729
Print ISSN : 0021-1699
ISSN-L : 0021-1699
Systemic Therapy for Anovulatory Sterile Women
Ryozo TOTANINobuhiko SAIKI
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1974 Volume 28 Issue 2 Pages 121-126

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Abstract
Sterile women with suspected ovarian dysfunction were tentatively classified on the basis of the BBT and the periodicity of menstruation, and a systemic treatment was applied for the induction of ovulation in each group.
This paper presents some results which have been obtained in our clinic from Dec. 1970 to Nov. 1972.
Reliable BBT were obtained with 622 cases, of which 65.5% belonged to regular diphase-eumenorrhea, and 18.0% to low monophase: the latter is seldom associated with spontaneous ovulation.
The Kaufmann therapy was performed in 29 cases (one course for each case), and the rebound phenomenon was noted in 9 cases, of which 4 became pregnant. A total of 387 cycles of clomiphene were administered to 109 cases, and 34 became pregnant.
The HMG-HCG therapy was applied to 24 cases, in which the clomiphene therapy had previously been ineffective. Ovulation were noted in 12 cases, 3 became pregnant during the administration, and additional 4 pregnancies were found in half a year. Of the whole pregnancies found within the two year observation period, about 40% were considered to be the effective cases for our ovulation-induction therapy
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© Japanese Society of National Medical Services
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