Abstract
We checked HLA antigens in order to study the immuno-genetic relations in the in-flammatory bowel diseases (IBD). The study was done on seven patients, including four cases of ulcerative colitis (UC), two cases of Crohn's disease (CD) and one case of intes-tinal tuberculosis (TB) who were treated in our hospital.
The typing of A, B and C antigens was made after the NIH standard method using commercially available “HLA-A, B, C plate HS” by Hoechst Japan KK, Tokyo.
Three out of four cases of UC had AW 24 and CW 3 and two cases demonstrated A 11 and BW 52. Two cases of CD had only CW 3. One case of TB had AW 24.
These results suggested that AW 24, CW 3, A 11 and BW 52 were important in UC. There were no specific findings in CD and TB except for CW 3 and AW 24 respectively. We would like to continue this study and to collect more data in the future
