Abstract
Experimental study was conducted on the effects of intramuscular injection of cow-milk (5cc, verey other day) in normal male white rabbits, and the following results were obtained.
1. Subsequent to the initial injection, the Indian ink particle phagocytosis of pseudoeosiophile cells were accele. ated in every case. Generally, the phagccytosis showed off temporarily by the following day of he second injection, and the maximum phagccytosis was observed by the 2nd-4th day of the second injection. The accelerated phagocytosis gradually fell off to the original level by 10 days after the 2nd injection.
2. The amount of serum globulin increased gradually subsequent to the 1st and 2nd injection. It showed the maximum level by 1st-4th day after the 2nd injection and gradually fell off to the original level by around 13 days.
3. The rate of pseudo-eosincphile cell became the highest figure by the 1st day subsequent to the 1st injection. It temporarily became at the original figure by 3rd-6th day and it was at that figure or smaller level during the 15 days of the experiment.
4. As for nuclear shift of the pseudo-eosinophile cells, left shift was observed subsequent to the 1st injection and more left shift was observed subsequent to the 2nd injection. In around 2 weeks, nuclear shift recovered.
5. Concentration of acid fuccin in the aqua anterior decreased by 1 week after the 2nd injection and slightly increased during the following 2 weeks.
6. Preliminary immunization, by means of dead coli bacilli, was given to rabbits, to which cow-milk injection was conducted 7 weeks after the in munization. The agglutinin value of serum increaed by 1 week, however, that of aqua anterior did not. The production of aggultinin was remarkably restrained, in case of the concommitant performance of the immunization and the milk injection.
7. Body weights were intact, practically. Body temperature became slightly high degree, subsequent to the 1st and 2nd injections.
