Abstract
The clinical manifestations and HIV testing was analyzed in 137 patients with condylomata acuminata. A pulsed carbon dioxide laser was used to treat 60 patients and 0.15% podophyllotoxin cream was used in 30 patients. Condylomatous lesions were seen at a high rate (87.6%), and the number of patients testing positive for HIV was comparatively high (8%). The first pulsed laser carbon dioxide treatment gave a cure rate of 81.7% as compared with a 40% cure rate with topical cream (p < 0,001). Scars were noted in 8.3% of patients treated with pulsed carbon dioxide laser. The results of the study suggest that carbon dioxide laser is a safe, effective and easy-to-deliver therapeutic approach for the treatment of condylomata acuminata, and that the autosimultaneous LLLT component of laser radiation in the periphery of the photothermal destruction contributed greatly to this efficacy.