Abstract
Several kinds of wearable chemical sensors were constructed by micro-fabrication techniques for measuring biochemical substances. The wearable oxygen sensor was successfully used to monitor the transcutaneous oxygen pressure by applying the device onto the forearm skin surface. Tear fluid conductivity was possible to be measured by applying the wearable sensor to the human subject's temporal lower cul-de-sac. Bio-sniffer devices for several kinds of gaseous substances, such as ethanol, trimethylamine, were developed using enzyme immobilized membrane and a reaction cell with both gas and liquid phase compartments separated by a porous diaphragm membrane.