Abstract
We examined the effect of dried bonito protein koji hydrolysate (KH) intake on the lipid metabolism of rats fed a high-fat (HF) diet. The rats were divided into four groups. The first group was given the control diet, the second group, a HF diet containing 30% lard, the third group, a HF diet containing 5% KH, the fourth group, a HF diet containing 5% KHL (KHL : KH in which TFF was filtered). These experimental diets were given for 4 weeks. Consequently, the body and circumference (kidney) adipose tissue weights of the HF+KH and HF+KHL groups were lower than those of the HF group. The serum TG and NEFA levels of the HF+KH and HF+KHL groups were also significantly lower than those of the HF group. However, as regards serum cholesterol level, there was no difference between the four groups. The liver G 6 PD activities of the HF, HF+KH, and HF+KHL groups were higher than that of the control group. Moreover, the liver ACO activities of the HF+KH and HF+ KHL groups were in higher than that of the HF group. These results suggest that either KH or KHL intake accelerates the lipid metabolism of rats fed a high-fat diet.
