Role of Carbohydrates in Cell Adhesion and Recognition

Abstract

The molecular basis of cell adhesion is of fundamental importance for under standing differentiation, organization, and development in multicellular organisms, as well as numerous diseases and disorders involving abnormal cell adhesion . Out of five families of cell adhesion molecules, two (invol ving selectin-CHO and CHO-CHO interaction) have been reviewed in this lecture. U nderstanding of CHO-based adhesion events has important diagnostic and the rapeutic implications.