2017 Volume 66 Issue 5 Pages 530-537
There is currently no analytical device for conducting the rapid antimicrobial susceptibility test (AST). DPS192iX is a new commercial antimicrobial susceptibility analyzer. We evaluated the performance of DPS192iX for rapid AST. We used 199 isolates of gram-negative Enterobacteriaceae for analysis. We measured the minimum inhibitory concentration (MIC) at 6, 7 and 8 hours and 18 hours from the start of AST. Then, we compared the coincidence rates of MIC and interpretive categories. The percentages at which the MICs matched at 6, 7 and 8 hours were 66.4%, 69.3% and 71.0%, respectively. The agreement rates of interpretive categories after 6, 7 and 8 hours and 18 hours of culture were 87.4%, 88.7% and 90.2%, respectively. Then the proportions of very major errors at 6, 7 and 8 hours were 23.1%, 17.7% and 15.4%, respectively. The major error rates were 2.6%, 2.3% and 2.0%. The results of the rapid AST showed high agreement with the final results. Moreover, there was almost no discrepancy in the results. In conclusion, we have shown that DPS192iX may contribute to rapid AST.
