A case of serous carcinoma of uterine origin that postoperatively metastasized to the left thigh

Abstract

Serous carcinoma is a highly malignant histological type of uterine cancer with a poor prognosis. We reported a case of a serous carcinoma of uterine origin in which a metastatic focus formed a multilocular cyst on the posterior aspect of the left thigh 4 years after surgery. This case involved a woman in her 80s. MRI revealed that a multilocular cystic mass had formed on the posterior aspect of the left thigh, and part of the mass was solid. PET-CT revealed FDG uptake in the solid portion, and needle aspiration cytology was performed. Cytology revealed the appearance of atypical cells, but determining the cell origin was difficult. Immunohistological staining of cell blocks was performed, and results indicated malignant cells originating from epithelial cells. An open biopsy of the left thigh was subsequently performed. The patient had previously undergone a hysterectomy due to uterine cancer, so the final histological diagnosis was serous carcinoma of uterine origin that had metastasized to the left thigh. The current case involved distant metastasis of a malignant tumor in the field of gynecology. This was a rare case, since metastasis to the soft tissue of the thigh has seldom been reported, so it has been reported here.