Abstract
A thin-film coating of hexamethyldisiloxane (HMDSO) and an O2-plasma treatment were carried out on titanium (Ti) plates. The contact angle of HMDSO-coatings without O2-plasma treatment against double-distilled water was more than 100 degrees, and dramatically decreased after the O2-plasma treatment with less than 5 degrees, resulting superhydrophilicity. Cell proliferation and the alkaline-phosphatase activity of osteoblast-like cells increased on the surfaces of HMDSO-coating with O2-plasma treatment compared to on the Ti and HMDSO-coatings without O2-plasma treatment. SEM observation revealed that the cultured cells were spread on O2-plasma modified surfaces. These results indicated that HMDSO-coating with O2-plasma treatment was a promising for fabricating with osteogenesis surface of scaffolds.
