Journal of Oral Tissue Engineering
Online ISSN : 1880-0823
Print ISSN : 1348-9623
ISSN-L : 1348-9623
ORIGINAL ARTICLES
Study of Pluripotency and Activation of Totipotency in Human Adipose-derived Stem Cells
Shunji IZAWAKozo YAMAJIAkihito YOKOYAMAKumiko MATSUZAKINaoko OHARAMasahiro YOSHIYAMA
著者情報
ジャーナル フリー

2016 年 13 巻 3 号 p. 131-135

詳細
抄録

Tissue regeneration is the important issue in the field of operative dentistry. In the previous study, we demonstrated that TNFα activates the potential for totipotency in human bone marrow mesenchymal stem cells (hMSCs) and leads to the regeneration of target cells or tissues along with the appropriate differentiating factor such as Emd-Gel. In this study, we apply the transcription factor set of TNF-α and Amelogenin to the human adipose-derived stem cells (hASCs) and our results indicate that this transcription factor set differentiate hASCs into odontblasts simillary and suggest that TNFα activates potential totipotency of hASCs and the activation can lead to the regeneration of target cells or tissues

著者関連情報
© 2016 by Japanese Association of Regenerative Dentistry
前の記事 次の記事
feedback
Top