Abstract
The lipid compositions of serum lipoprotein (Lp) were determined by agarose gel electro phoresis and simple enzymatic method, at least a month after a myocardial infarction (MI) in 98 Patient, and the values obtained were compared with those in 79 healthy control subjects.
In total serum lipid, only triglycerides (TG) concentration in MI patients was significantly increased, and in Lp fractions, only HDL was singficantly decreased. In the lipids of HDL, choresterol (Chol) and phospholipids (PL) were decreased in these concentrations, TG was increased and Chol was decreased in the distribution ratios.
In LDL and VLDL, all lipid concentrations were significantly increased, but in the distribution ratios, chol was decreased in LDL, PL was decreased in VLDL.
When compared these distribuation ratios in the limitation of normal lipid level, Chol and PL in female in HDL, TG and Chol in male in LDL and PL in male and TG in female in VLDL showed significant difference. In the high TG level, however, there were marked differences in TG in both male and female and in Chol in male.
These changes of the Lp composition in HDL had significant correlations with serum TG levels, and it suggeted that the disorder of serum TG metabolism had some relation with those changes.
