Studies on Various Factors Relating to Serum High Density Lipoprotein Cholesterol Levels

Abstract

HDL-Cholesterol (HDL-C) level was measured in relatively large number of subjects, and it was compared with other factors which were supposed to be related to serum HDL-C levels. In the present studies, the following results were obtained.
(1) HDL-C level was negatively corelated with atherogenic Index, pre-β+β/α ratio, plasma triglyceride levels and obesity Index for both sexes, and positively co-related with plasma PL levels for both sexes, and plasma T. C. and FFA levels for women.
(2) While the subjects with both obesity and hypertriglyceridemia demonstrated marked decrease of HDL-C levels, the subjects with only hypertriglyceridemia (not obese) demonstrated relative decrease of HDL-C levels compared with normal subjects. On the contrary, subjects with only obesity (not with hypertriglyceridemia) did not show decrease of HDL-C levels.
(3) While mean HDL-C level was significantly higher in the alcoholic subjects and the more the alcoholic intake, the higher the HDL-C level.
(4) While mean HDL-C level was significantly lower in the subjects with heavy cigarette smoking, mean triglyceride level was higher in the smoking subjects.
(5) The subjects with abnormal electrocardiography (non specific ST, T Change) did not demonstrate decrease of HDL-C level compared with normal subjects.