抄録
Effects of aerobic exercise on coronary risk factors were assessed in patients with obesity, hyperlipoproteinemia, or glucose tolerance abnormality.
METHODS: Aerobic exercise program was prescribed on patients with obesity (18 males and 3 females, age: 22-64, mean 46.1±2.33 (S.E.) years), hyperlipoproteinemia (28 males, 5 females, 27-57, 43.0±1.62 years, Type IIa 16, IIb 11, IV 3, low HDL-cholesterol 3 cases), non-insulin dependent diabetes (5 males, 3 females, 37-64 years) or impaired glucose tolerance (12 males, 1 female, 40-57 years) (mean 50.3±1.31 years). Physical fitness classification of the patients was determined by submaximal treadmill stress testing following Balke's protocol. In some cases, their oxygen uptake was directly indicated continuously employing Waters Oxygen Consumption Computer MRM-1, during the treadmill testing. In accordance with the category of fitness, aerobics exercise program was prescribed following Cooper, K. H. (1970, 1977), Cooper, M. and Cooper, K. H. (1972). The prescription was designed to be selected among the equivalent exercise programs of walking, running, cycling, swimming, stationary running/cycling, rope skipping and other various sports. After completing several weeks' program, traedmill test was performed and the program was renewed to be compatible with the new fittness category. Body weight, serum lipids level, oral 75g glucose tolerance test (OGTT) and oxygen uptake determined by treadmill testing were assessed before and on the exercise program to compare the differences statistically.
RESULTS: 1) Body weight: Improvement in obesity index was observed concomitantly with increase in oxygen uptake (obesity index: before program+(18.9±1.83)%, on program+(15.8± 5.86)%, P<0.05, oxygen uptake: before program 7.9±0.55 METS, on program 9.5±0.60 METS, P<0.01). 2) Serum lipids level: Decrease in serum total cholesterol (TC) level was observed concomitantly with increase in oxygen uptake (TC: before program 276.1±12.17, on program 240.3±11.10mg/dl, P<0.01, oxygen uptake: before program 7.5±0.73, on program 8.9±0.81 METS, P<0.01). 3) OGTT: Decrease in blood sugar level on OGTT at 120 minutes (OGTT BS 120′) and sigma BS (∑BS) were observed concomitantly with increase in oxygen uptake (OGTT BS 120′: before program 162.9±9.51, on program 118.6±9.68mg/dl, P<0.01, ∑LBS: before program 931.6±48.04, on program 806.6±25.41mg/dl, P<0.01, oxygen uptake: before program 6.8±0.75, on program 8.5±0.91 METS, P<0.01).
COMMENT: Beneficial effects of aerobics exercise on coronary risk factors were suggested.
