抄録
Glycosylated-LDL was prepared by incubation of human LDL with glucose and galactose in vitro. The glycosylated-LDL containing more than 20 to 25 percent of free amino group modified, was metabolized at a slow rate by both human skin fibroblasts and mouse peritoneal macrophages. From the fractional catabolic rates of glucose-LDL and galactose-LDL, catabolism by a receptorindependent process occured 41 and 30 percent respectively. These results suggested that glycosylated-LDL was a useful tool in estimating receptor-independent LDL catabolism.
