糖尿病における血清シアル酸

―とくに血清脂質との関連性について―

抄録

Serum sialic acid and lipid concentration weremeasured in 17 healthy controls, in 13 hyperlipidemic subjects, and in 42 diabetic subjects. In diabetic subjects there was a significant increase in age, fasting plasma glucose, total cholesterol (TC), triglyceride (TG), and LDL-cholesterol (LDL-ch) as compared with those in healthy controls. But there was no significant difference inserum sialic acid and HDL-cholesterol. In female diabetic subjects a significant positive correlation was observed between sialic acid andTC, TG.
In female diabetic subjects with hyperlipidemia there was significant increase in sialic acid, TC and LDL-ch than healthy controls, hyperlipidemia and diabetic subjects without hyperlipidemia and a significant positive correlation between sialic acid and TG in type IIb hyperlipidemia.
From these observasions we suggest the correlation between sialic acid and lipid concentrasion in diabetic subjects.