抄録
Cardiocerebral apoplexy is nowadays applied to a syndrome of atypical acute myocardial infarction with cerebrovascular accident with a little vagueness in the definition. Ozawa and Fujii found by considerable reserches that this syndrome develops in the aged over 70 and that some cases reveal macroscopical findings of encephalomalacia in autopsy and others lack of those. But this syndrome is wanting pathological basis because of lack of detailed histopathological examination of its case.
For the purpose of investigating the pathogenesis of this syndrome, we studied microscopically cardiac lesions in cases of cerebrovascular diseases (cerebral hemorrhage, subarachnoid hemorrhage) and obtained histopathological findings of the heart which could explain the bringing about of this syndrome.
(1) There was no complication of myocardial infarction in all cases of cerebral hemorrhage and subarachnoid hemorrhage in our cases.
(2) Marked myocardial fibrosis was revealed in 10 (37%) out of 27 cases of cerebral hemorrhage and slight myocardial fibrosis was showed in all 9 cases of subarachnoid hemorrhge.
On the contrary, in cerebral infarction studied by Iida there was complication of myocardial infarction in 18 (29%) out of 62 cases and was marked myocardial fibrosis in 21 (60%) out of 35 cases.
Our reserches showed that there are differences in the degree of occurrence of coronary insufficiency between cerebral hemorrhage and subarachnoid hemorrhage and cerebral infarction. They explained that it should be understood that cardiocerebral apoplexy is formed on the basis of severe coronary insufficiency in cerebrovascular disease.
