抄録
Total cholesterol (TCH), triglyceride (TG), HDL-cholesterol (HDL-CH), LDL-cholesterol (LDL-CH) and atherogenic indices (AI1=TCH-HDL-CH/HDL-CH, AI2=LDL-CH/HDL-CH) were studied in 971 healthy Japanese male inhabitants of Tokyo, Kawasaki, Mizushima and Takaoka.
HDL-CH was significantly lower in Takaoka (49±11mg/dl) and in Mizushima (52±11mg/dl) than in Tokyo (58±13mg/dl) and in Kawasaki (58±14mg/dl). The area difference of HDL-CH was very similar to that of TG, but not to that of TCH.
Atherogenic indices were significantly higher in Takaoka (2.93±0.86, 2.44±0.75) and in Mizushima (2.84±0.79, 2.28±0.66) than in Tokyo (2.61±0.81, 2.00±0.69) and in Kawasaki (2.38±0.90, 1.75±0.81).
The prefectural mortality due to cardiac or cerebrovascular disease in 1978 was higher in the area with lower HDL-CH or with higher atherogenic indices. This suggested a clinical and epidemiological value of HDL-CH and atherogenic indices.
