抄録
Twenty patients with hyperlipidemia (total cholesterol≥220mg/dl) were treated with γ-Oryzanol of 300mg/day for 16 weeks, during which time changes in serum lipid levels were observed.
Both total cholesterol and HDL-cholesterol were reduced significantly within 4 and 12 weeks, respectively, following the treatment with γ-Oryzanol, with the degree of changes in both being almost identical. Therefore, the atherogenic index was not significantly changed.
Levels of triglycerid and β-lipoprotein were significantly reduced at 12 and 16 weeks following medication, respectively, while those of phospholipid and free fatty acid were unchanged.
No complications were found in any of the patients with this medication.