Abstract
A histological and bacteriological studies and the observation of pH fluctuation were made with bronchial secration in broncho-pulmonary tuberculosis by instilling the streptomycin to the affected region for 10 month, and following results were obtained.
1) The pH of bronchial secration was between 6.4 and 9.0, which is between slight acidity and alkalinity.
2) The pH of bronchial secration was almost neutral in mild cases (the first and second stage), and it fluctuated from slight acidity to slight alkalinity in severe cases (the second and third stage). An ulcer was noted in the case of slight acidity and cavity or hypersecretion in slight alkalinity.
3) pH was inclined so approach to neutrality when treatment was given, but in ulcerative cases such tendency was not recognized.
4) In the mixed infection bacilli were abundant in alkalin reaction, and showed signs of ebbing with alteration from neutrality to acidity.
5) When the secretion showed alkalin reaction, many polynuclear leukocytes and histiocytes were present. However, they were decreased as it approached to the neutrality.
