Atrophy of Esophageal Mucosa with Referrence

To the So-called Plummer-Vinson's Syndrome and Predisposition of Carcinoma of the Esophagus

Abstract

In patients complaining of difficulty in swallowing, iron deficiency was found in 18 patients on whom endoscopic examination, biopsy of mucosa of the upper esophagus, radiographic studies and measurement of the inner pressure of the esophagus were performed. The results were as follows:
1) Endoscopic findings: The mucosa, in general, was pale and atrophic and vessels were visible and transverse folds were numerous.
2) Biopsy findings: Atrophic changes of the mucosa was prominent, and atrophy and degeneration of muscular fibers were also found.
3) Radiographic findings: In many cases was found a web-formation in the lumen of the esophagus.
4) The inner pressure curve: It was proved that peristalsis of the esophagus was reduced.
5) Review of literature: Reviewing the litera ture, discussion on Plummer-Vinson's syndrome and predisposition of carcinoma of the esophagus were described.