We reported a case of invasive laryngeal carcinoma arising in preexisting big laryngeal papillomatosis.
A-59-year-old man complained of increasing hoarseness and dyspnea before tracheotomy. We noticed huge tumor in the larynx. Pathological diagnosis was papilloma at the first examination. Because of recurrence of the tumor, frequent management by dioxide laser surgery was required to maintain an adequate airway every 2-month. At the fourth time biopsy, the histological diagnosis was epidermoid carcinoma. Papilloma virus was also found in carcinoma. For radical treatment, total laryngectomy was done, and his clinical course is very good for two years after surgery.
Some discussions were made concerning the classification, etiology, transformation into carcinoma and treatment of papilloma.
