抄録
Recently, the incidence of multiple primary esophageal cancer (MPEC) has increased. During the 5 yearsfrom 1992 to 1996, the percentage of MPECs which underwent resection at the National Cancer Center was39.0%. The frequency of esophageal cancer associated with head and neck cancer has especially increased. For the early detection of second primary esophageal cancer, an endoscopic examination with Lugol stain should be made routinely after treatment for head and neck cancer.