Journal of Biomedical Fuzzy Systems Association
Online ISSN : 2424-2578
Print ISSN : 1345-1537
ISSN-L : 1345-1537
Changes in Therapeutic Time and Patient Outcomes in Acute Stroke Care with Primary Stroke Center
Miwa KIKUCHI , Manami NIIYAMA
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2026 Volume 27 Issue 2 Pages 11-19

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Abstract
[OBJECTIVE] To examine the impact of Primary Stroke Center (PSC) certification on therapeutic time and patient outcomes in acute stroke care. [METHODS] We retrospectively analyzed 82 patients who underwent intravenous rt-PA or endovascular thrombectomy between April 2018 and March 2021. Therapeutic time indicators included Door-to-Image Time (DIT), Door-to-Needle Time (DNT), Door-to-Puncture Time (DPT), and Door-to-Recanalization Time (DRT). Patient outcome was assessed using the modified Rankin Scale (mRS) at 3 months after onset. [RESULTS] After PSC certification, DIT (p=0.022), DNT (p=0.001), and DPT (p=0.029) significantly decreased, whereas DRT and 3-month mRS showed no significant difference. [CONCLUSIONS] PSC certification was suggested to improve clinical processes and effectively reduce the time to treatment initiation. Continuous efforts are needed to further shorten therapeutic time and to identify factors influencing patient prognosis.
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© 2026 Biomedical Fuzzy Systems Association
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