A Case of Severe Friction Melanosis Improved by Intake of Food Containing Hot Water Extract of Coix lacryma-jobi L. var. ma-yuen Stapf with Husks

Abstract

Friction melanosis is a cutaneous entity characterized by a brownish pigmentation distributed on the skin over bony regions of various sites including a trunk or the limbs. In this report, we presented the case of a 44-year-old woman who developed severe friction melanosis around both knees and lower extremities for about 10 years. Coix-seed Reactive Derivatives (CRD) was administrated orally 4.0 g/day for 20 weeks and the lesions of pigmentation improved moderately. Further research is needed to define the optimal duration of CRD intake against friction melanosis.