J-STAGE Home  >  Publications - Top  > Bibliographic Information

Journal of Clinical Biochemistry and Nutrition
Vol. 48 (2011) No. 1 P 68-71

Language:

http://doi.org/10.3164/jcbn.11-012FR

Reviews

Diabetes mellitus increases the risk of heart failure independently of underlying coronary artery disease. It also causes skeletal muscle dysfunction, which is responsible for reduced exercise capacity commonly seen in heart failure. The underlying pathogenesis is partially understood. Several factors may contribute to the development of cardiac and skeletal muscle dysfunction in heart failure and diabetes mellitus. Based on the findings in animal models, this review discusses the role of oxidative stress that may be involved in the development and progression of cardiac and skeletal dysfunction associated with diabetes.

Copyright © 2010 by The Editorial Secretariat of JCBN

Article Tools

Share this Article