Journal of Clinical Biochemistry and Nutrition
Online ISSN : 1880-5086
Print ISSN : 0912-0009
ISSN-L : 0912-0009
Original Articles
A fermented barley and soybean formula enhances skin hydration
Sein LeeJong-Eun KimSujin SukOh Wook KwonGaeun ParkTae-gyu LimSang Gwon SeoJong Rhan KimDae Eung KimMiyeong LeeDae Kyun ChungJong Eun JeonDong Woon ChoByung Serk HurhSun Yeou KimKi Won Lee
Author information
JOURNAL FREE ACCESS
Supplementary material

2015 Volume 57 Issue 2 Pages 156-163

Details
Abstract

Skin hydration is one of the primary aims of beauty and anti-aging treatments. Barley (Hordeum vulgare) and soybean (Glycine max) are major food crops, but can also be used as ingredients for the maintenance of skin health. We developed a natural product-based skin treatment using a barley and soybean formula (BS) incorporating yeast fermentation, and evaluated its skin hydration effects as a dietary supplement in a clinical study. Participants ingested a placebo- (n = 33) or BS- (3 g/day) containing drink (n = 32) for 8 weeks. A significant increase in hydration in the BS group as compared to the placebo group was observed on the faces of subjects after 4 and 8 weeks, and on the forearm after 4 weeks. Decreases in stratum corneum (SC) thickness were also observed on the face and forearm. BS enhanced hyaluronan (HA) and skin barrier function in vitro and reduced Hyal2 expression in human dermal fibroblasts (HDF). BS also recovered ultraviolet (UV) B-induced downregulation of HA in HaCaT cells. These results suggest that BS has promising potential for development as a health functional food to enhance skin health.

Content from these authors
© 2015 JCBN
Previous article Next article
feedback
Top