Immunomodulating Compounds in Basidiomycetes

Masashi Mizuno; Yosuke Nishitani

doi:10.3164/jcbn.13-3

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Immunomodulating Compounds in Basidiomycetes

Masashi Mizuno, Yosuke Nishitani

著者情報

キーワード: Basidiomycetes, β-glucan, immunomodulating activity, antitumor activity, polysaccharide

ジャーナルフリー早期公開

論文ID: 13-3

DOI https://doi.org/10.3164/jcbn.13-3

この記事には本公開記事があります。

The final version of this article is now available: Vol. 52 (2013), No. 3 pp. 202-207

詳細

抄録

Mushrooms are distinguished as important food containing immunomodulating and anticancer agents. These compounds belong mostly to polysaccharides especially β-d-glucans. Among them, β-1,3-glucan with side chain β-1,6-glucose residues have more important roles in immunomodulating and antitumor activities. In this review, we have introduced polysaccharide mainly from Lentinula edodes and Agaricus blazei Murill with immunomodulating and antitumor activities. In addition, the mechanism of activation of immune response and signal cascade are also reviewed.

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