Abstract
Effects of vitamin A deficiency on vitamin E were evaluated in two different situations in which the vitamin A intake was notably reduced. On the one hand, dogs on an equilibrated diet were submitted to intestinal resection; hence vitamin A was poorly absorbed, compared with a control group. On the other hand, deficit of vitamin A was provoked in rats feeding them with a vitamin A-deficient diet. In both cases vitamin A plasma levels were decreased on comparing them with the corresponding control groups. In these two cases symptoms of vitamin A deficiency were observed as loss of muscular mass and nephrolithiasis. It is interesting to point out that when vitamin A was depleted by either of the methods, the vitamin E plasma level noticeably increased.