Journal of Clinical Biochemistry and Nutrition
Online ISSN : 1880-5086
Print ISSN : 0912-0009
ISSN-L : 0912-0009
Effects of Vitamin A Deficiency on Vitamin E
Felix GRASESManuel ZURITACatalina GENESTARRamon GARCIA-GONZALEZ
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1995 Volume 18 Issue 2 Pages 119-125

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Abstract
Effects of vitamin A deficiency on vitamin E were evaluated in two different situations in which the vitamin A intake was notably reduced. On the one hand, dogs on an equilibrated diet were submitted to intestinal resection; hence vitamin A was poorly absorbed, compared with a control group. On the other hand, deficit of vitamin A was provoked in rats feeding them with a vitamin A-deficient diet. In both cases vitamin A plasma levels were decreased on comparing them with the corresponding control groups. In these two cases symptoms of vitamin A deficiency were observed as loss of muscular mass and nephrolithiasis. It is interesting to point out that when vitamin A was depleted by either of the methods, the vitamin E plasma level noticeably increased.
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