Abstract
We compared plasma lipids, lipoproteins, platelet aggregation, plasma lipase activity, age, and body mass index (BMI) between patients with non-insulin-dependent diabetes mellitus and non-diabetic controls. Diabetic subjects showed significantly higher levels of plasma total triglycerides (TG) and very-low-density lipoprotein cholesterol (VLDL-C) and significantly increased platelet aggregability. The total cholesterol (TC)/high-density lipoprotein cholesterol (HDL-C) ratio was also significantly higher consequent to the significantly lower HDL-C levels in the diabetic subjects when compared with non-diabetic controls. The diabetic group showed positive significant correlations between TC and low-density lipoprotein cholesterol (LDL-C), HDL-C and plasma lipase activity, and TG and TC/HDL-C ratio, whereas significant inverse correlations were observed between TG and HDL-C, HDL-C and TC/HDL-C ratio. Platelet aggregation did not correlate significantly with any of the metabolic variables studied in this group.
