βリン酸三カルシウム/ポリ乳酸共重合体複合体中の化学的相互作用

抄録

For the development of a novel biodegradable membrane useful for surgical operations, the chemical interaction between β-tricalcium phosphate (TCP) and copolymerized poly-L-lactide (CPLA) in the TCP/CPLA composites was investigated by Fourier-transformed infrared spectroscopy (FT-IR) and dynamic mechanical analysis (DMA). From FT-IR measurements, chemical interaction between Ca²⁺ in TCP and O^δ- of ester C=O double bonds in CPLA was detected as the red shift of C=O stretching vibration mode. DMA measurements showed that the storage and loss elastic moduli of the composites increased with increasing in TCP content, corresponding to the strength change in Ca²⁺…O^δ-(=C^δ+) interaction, though glass-transition and softening temperatures did not change. The mechanical and thermoplastic properties of the composites were highly suitable for a guided-bone-regeneration membrane.