抄録
Siloxane-containing vaterite doped with magnesium (MgSiV) was prepared by a carbonation process for application in bone regeneration. Ca(OH)2, aminopropyltriethoxysilane (APTES) and Mg(OH)2 were mixed with a solvent consisting of methanol and distilled water under CO2 gas. After the mixture was aged, the translucent precursor gel was dried, resulting in the formation of MgSiV particles containing 2.0 wt % magnesium and 2.8 wt % silicon. The MgSiV consists of distorted spherical particles with diameters of approximately 1.3 µm and a thickness of approximately 0.6 µm while the siloxane-containing vaterite without magnesium (SiV) was spherical with a diameter of approximately 1.5 µm. X-ray diffraction (XRD) analysis suggests the incorporation of magnesium into the vaterite structure. Fourier transform infrared spectroscopy (FTIR) indicated the presence of amorphous calcium carbonate (ACC) while the magnesium and the siloxane formed Si–O–Mg bonds. After heating the MgSiV at 500°C, the magnesium removed from the vaterite structure formed Si–O–Mg bonds with the siloxane. The MgSiV released Ca2+, Mg2+ and Si4+ ions into a Tris buffer solution. The amount of Ca2+ ion dissolved in the Tris buffer solution increased within the initial 12 h and subsequently decreased with time because of the formation of precipitates.
