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Antimicrobial and antiviral activity of proton-type zirconium phosphate
論文ID: 25123
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論文ID: 25123
Antibacterial and antiviral inorganic materials are attracting increasing attention for their biomedical and environmental applications. This study aimed to examine the antibacterial and antiviral properties of zirconium phosphate powders, Zr(HPO4)2·H2O, Zr(PO4)(H2PO4)·2H2O, HZr2(PO4)3, and (H3O)Zr2(PO4)3, and to clarify the role of pH in their activity. Antibacterial activity against Escherichia coli was confirmed in Zr(PO4)(H2PO4)·2H2O, HZr2(PO4)3, and (H3O)Zr2(PO4)3 powders; high antiviral activity against the bacteriophage Qβ was detected in Zr(PO4)(H2PO4)·2H2O and (H3O)Zr2(PO4)3 powders, with the antiviral activity of Zr(PO4)(H2PO4)·2H2O being superior to that of (H3O)Zr2(PO4)3. After immersion in deionized water for 1 d, the pH values of the Zr(PO4)(H2PO4)·2H2O, HZr2(PO4)3, and (H3O)Zr2(PO4)3 powders reduced to 3.64, 4.41, and 3.99, respectively, becoming lower than that of Zr(HPO4)2·H2O (5.12). The observed effects were attributed to the lower pH caused by the formation of H3O+ upon contact with water. These results demonstrate that acidity is crucial in the antibacterial and antiviral functions of zirconium phosphate-based materials, providing insights for the design of functional inorganic antimicrobial agents.
