抄録
To investigate the effects of serum markers on metabolic activities associated with both the formation and the resorption of bone, a biochemical study of the serum carboxyterminal propeptide of type I procollagen (P I CP) and the cross-linked carboxyterminal telopeptide of type I collagen (I CTP) was performed for disorders of bone metabolism. Serum P I CP and I CTP statistically increased in patients with the chronic renal failure, in who experienced hypercarcemia due to secondary hyperparathyroidism associated with a malignant tumor, bone metastasis, and Basedow's disease as compared with the normal group. Our results suggest that serum P I CP and I CTP may be useful as indicators of bone metabolic activities.
