Abstract
In this tutorial review, the principle of flow ratiometry and its application to flow titration are described. Throughput rate of the titration is greatly increased by combining feedback-based control and fixed triangular wave control, where the scan rate and scan range in the latter mode are respectively steeper and narrower than those in the former mode. Unprecedented high throughput rate (maximally 34 titrations per minute, corresponding to 1.76 second per titration) with reasonable precision (RSD < 0.5 %) has been achieved by this approach.
