Journal of General and Family Medicine
Online ISSN : 2189-7948
Print ISSN : 2189-6577
ISSN-L : 2189-6577
Case Reports
Cronkhite-Canada Syndrome with Complete Remission after Four Months of Prednisolone Therapy and Polypectomy
Hiroki NamikawaYasuhiko TakemotoNoriko KamataMasakazu YashiroKazuhiro HirohashiTaichi Shuto
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2015 年 16 巻 4 号 p. 297-301

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The etiology of and optimal treatments for Cronkhite-Canada syndrome (CCS) are still undetermined. Fewer than 5% of CCS patients experience complete remission and 15% of CCS patients develop malignancies. Here, we present a case of CCS involving autoimmune disorders, in which rapid diagnosis, rapid commencement of therapy, and complete remission were achieved after 4 months of prednisolone therapy and polypectomy, although biopsy specimens from all residual colonic polyps revealed adenocarcinoma in one polyp 4 months after prednisolone therapy. It is important to identify gastrointestinal or colonic polyps harboring malignant changes and to examine the involvement of autoimmune mechanisms for better outcomes in CCS patients.
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© 2015 Japan Primary Care Association
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