The Effect of Cow-Bone-Powder on Osteopenia of Rat Model of Postmenopausal Osteoporosis

Abstract

This study was designed to test the effect of cow-bone-powder on skeletal metabolism of rat model of postmenopausal osteoporosis.
SD-strain female rats weighing about 100 g were ovariectomized and fed on a low calcium diet (0.003% Ca, 0.3% P) for 22 days. The rats were then divided into two groups, CaCO₃ diet fed rats and cow-bone-powder diet (containing 0.3% calcium and 0.3% phosphorus) fed rats for 27 days.
Compared with the rats fed with CaCO₃ diet, the rats fed with the cow-bone-powder diet showed a significant increase in 1) the calcium content of the femur, 2) the breaking-force of the femur, 3) the number and activity of bone trabecula mass.
The cow-bone-powder may be more suitable as a source of dietary calcium for the skeletal metabolism of postmenopausal osteoporosis than CaCO₃.