Abstract
Zinc, copper, iron and chromium are essential trace elements. The daily intake of these trace elements is insufficient. It is most likely that the deficiency of zinc, copper, iron and chromium is associated with life - style related diseases and aging. Actually, an increase in free radicals, a decrease in immunocompetence, an increase in blood pressure, the disorder of lipid metabolism, a reduction in glucose tolerance and a rise in carcinogenesis etc. are observed in both aging and the deficiency of the essential trace elements. Thus, the measurements of serum zinc, copper, iron and chromium in health examinations are available for the prevention of life - style related diseases and aging.