Abstract
The number of people afflicted with diabetes mellitus is increasing rapidly in Japan. Obesity associated with deteriorated life style is an important predictor and cause of diabetes mellitus. According to national survey, amount of exercise is decreasing in both men and women in Japan. Life style modification is mandatory to prevent diabetes and to control hyperglycemia in diabetic patients. DCCT and UKPDS successfully demonstrated that glycemic intervention leads to the prevention of microvascular complications. UKPDS80 demonstrated that early intervention in glycemia have long term beneficial effects in the prevention of microvascular and macrovascular complications. Early intervention seems to be very important in treating patients with diabetes mellitus. HbA1c value is going to be changed from JDS to NGSP value from April 1st, 2012.
