Abstract
CKD is a syndrome of renal dysfunction, which defined with abnormality of renal function and decrease in eGFR calculated by serum creatinine, gender, and age. In Japan, there are more than 13,300,000 CKD patients and ESRD patients increased up to 300,00. Therefore we are prompt to act for CKD prevention. Clinical Practice Guidebook for Diagnosis and Treatment of CKD 2012 is published this June in Japan from Japanese Society of Nephrology and is expected for the treatment of CKD. The major points of changes between this new guidebook and former guidebook are Classification of the CKD stage, formula of eGFR, Treatment strategy for hypertension with CKD. This Guidebook is hoped to change the better CKD prognosis.