Health Evaluation and Promotion
Online ISSN : 1884-4103
Print ISSN : 1347-0086
ISSN-L : 1347-0086

This article has now been updated. Please use the final version.

Asymptomatic Uterine Fibroid Associations with Nulliparity, Hypertension, and Obesity in Japanese Women
Fumio SatouTadashi AraiKazunari Hashiguchi
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JOURNAL OPEN ACCESS Advance online publication

Article ID: 2024-31

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Abstract

 Objective: We investigated associations between asymptomatic uterine fibroids and nulliparity, hypertension, and obesity in Japanese women.

 Methods: Japanese women who visited our health check-up center were enrolled between April 2021 and March 2022 and divided into two groups based on transvaginal ultrasound examination results: women with and without uterine fibroids (1,286 participants each, 2,572 participants in total). Their number of births, blood pressure levels (mmHg), and body mass index (BMI) (kg/m2) were compared.

 Results: In comparisons of women with and without uterine fibroids, nulliparity was 22.9% vs. 11.6%, p < 0.001; hypertension was 22.4% vs. 12.9%, p < 0.001; and BMI (25.0–29.9 kg/m2) was 14.8% vs. 10.9%, p = 0.004. Logistic regression analysis revealed that the odds ratios and 95% confidence intervals for nulliparity, hypertension, and BMI were 2.74 (2.04–3.67), p < 0.001; 1.43 (1.16–1.76), p < 0.001; and 1.30 (1.02–1.66), p = 0.035, respectively.

 Conclusion: We found that Japanese women with asymptomatic uterine fibroids had higher rates of nulliparity, hypertension, and obesity (1st degree) than those without uterine fibroids.

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