Abstract
The aim of this study was to clarify the validity and efficacy of cancer screening in the Multiphasic Health Testing and Services (MHTS) . A total of 19, 922 people visited our Health Evaluation Center for MHTS between 1995 and 1996. There were 14, 422 males who all received chest X-rays, barium meal, abdominal ultrasonography, and single-day immunological fecal occult blood test, and 5, 500 females who additionally received palpation of mamma, and uterine cervical cytology. By collating the Osaka cancer registry with the examinee's list, the cancer cases with unknown results of further examination, the false negative cancers, the progressive stage, the treatment and so forth were clarified. Esophageal cancer, gastric cancer, hepatic cancer, biliary tract cancer, pancreatic cancer, renal cancer, colon cancer, breast cancer, and uterine cervical cancer were defined as cancers detected by the MHTS. A detected cancer was defined as a cancer registered within one year after a positive result of the screening. A false negative cancer was defined as a cancer registered within one year after a negative result of the screening. As a result, the prevalence of the cancer was 0.225%. The sensitivity was 73.3% and the specificity was 81.3%. With regard to the progressive stage of the detected cancer, localized cancer (no metastasis) or carcinoma in situ accounted for 78.8%. The existence of cancer with neighboring organ invasion or distant metastasis was not described. With regard to the treatment of the detected cancer, a curative resection was done in 84.8%. It is expected that the stage of the detected cancer in the MHTS is comparatively early and the possibility of the curative resection is high.
