エナメル上皮腫におけるHSP27の免疫組織化学的観察

藤田 宗輝; 中野 敬介; 前田 初彦; 吉田 和加; 鳥居 亮太; 芳山 昌典; 岡藤 範正; 長谷川 博雅; 川上 敏行

doi:10.2485/jhtb.20.289

Original

Immunohistochemical Observation of HSP27 in Ameloblastomas

Muneteru Fujita, Keisuke Nakano, Hatsuhiko Maeda, Waka Yoshida, Ryota Torii, Masanori Yoshiyama, Norimasa Okafuji, Hiromasa Hasegawa, Toshiyuki Kawakami

Author information

Muneteru Fujita
Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
Keisuke Nakano
Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
Department of Oral Pathology, Matsumoto Dental University School of Dentistry
Hatsuhiko Maeda
Department of Oral Pathology, School of Dentistry, Aichi Gakuin University
Center for Advanced Oral Science, Aichi Gakuin University
Waka Yoshida
Department of Oral Pathology, School of Dentistry, Aichi Gakuin University
Center for Advanced Oral Science, Aichi Gakuin University
Ryota Torii
Department of Oral Pathology, School of Dentistry, Aichi Gakuin University
Masanori Yoshiyama
Department of Oral Pathology, School of Dentistry, Aichi Gakuin University
Norimasa Okafuji
Clinical Evaluation Unit, Matsumoto Dental University Graduate School of Oral Medicine
Hiromasa Hasegawa
Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine
Department of Oral Pathology, Matsumoto Dental University School of Dentistry
Toshiyuki Kawakami
Hard Tissue Pathology Unit, Matsumoto Dental University Graduate School of Oral Medicine

Keywords: Heat Shock Protein 27, HSP27, Immunohistochemistry, Ameloblastoma

JOURNAL FREE ACCESS

2011 Volume 20 Issue 4 Pages 289-294

DOI https://doi.org/10.2485/jhtb.20.289

Details

Abstract

We examined expression of Heat Shock Protein 27 (HSP27) molecules, in 10 cases of typical solid/multicystic ameloblastoma, by means of immunohistochemistry. In general, HSP27 and pHSP27 positive staining products were frequently detected in the cytoplasms of the neoplastic cells. The expression pattern and/or strength are slightly different according to the cytological features of ameloblastomas. The immunohistochemical staining results suggest that the expression of HSP27 and pHSP27 is considered to be involved in neoplastic transformation of odontogenic epithelial cells.

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